FOXO4 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements(IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells(ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. Immunogen: forkhead box O4 Synonyms: AFX, AFX1, MLLT7 Observed MW: 45-48kd Uniprot ID: P98177 Reactivity: Human, Mouse Tested Application: ELISA, WB, IF Recommended dilution: WB: 1: 500-1: 2000; IF: 1: 20-1: 200 Gene ID: 4303 Research Area: Epigenetics, Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience