IL10RA Antibody

Size : 50 µL Clone Number: Aliases: CD210 antibody; CDw210a antibody; CDw210a antigen antibody; HIL 10R antibody; HIL10R antibody; I10R1_HUMAN antibody; IL 10R 1 antibody; IL 10R A antibody; IL 10R antibody; IL 10R1 antibody; IL-10 receptor subunit alpha antibody; IL-10R subunit 1 antibody; IL-10R subunit alpha antibody; IL-10R1 antibody; IL-10RA antibody; IL10R antibody; IL10R1 antibody; IL10RA antibody; Interleukin 10 receptor alpha antibody; Interleukin 10 receptor alpha chain antibody; Interleukin-10 receptor subunit 1 antibody; Interleukin-10 receptor subunit alpha antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q13651 Immunogen: Fusion protein of Human IL10RA Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: IL10RA Research Areas: Immunology