DCSTAMP Antibody

Size : 50 µg Clone Number: Aliases: DC-STAMP antibody; DCSTAMP antibody; DCSTP_HUMAN antibody; Dendritic cell-specific transmembrane protein antibody; Dendrocyte-expressed seven transmembrane protein antibody; FIND antibody; hDC-STAMP antibody; IL-Four INDuced antibody; IL-four-induced protein antibody; Transmembrane 7 superfamily member 4 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9H295 Immunogen: Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC: 1: 200-1: 500, IF: 1: 50-1: 200 Background: Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: DCSTAMP Research Areas: Others